Desonide cream is a low-potency topical corticosteroid used to treat a variety of skin conditions, including eczema, dermatitis, allergies, and rash. It works by reducing inflammation, redness, itching, and swelling in the affected areas. Because of its mild strength, desonide is often prescribed for sensitive skin areas such as the face or in children when appropriate. It should be applied in a thin layer to the affected skin and used for the shortest duration necessary to manage symptoms, as prolonged use can lead to skin thinning or other side effects.