Ketoconazole is an oral anti-fungal agent used to treat systemic fungal infections. Ketoconazole treats susceptible systemic fungal infections including blastomycosis, histoplasmosis, paracoccidioidomycosis, coccidioidomycosis, and chromomycosis in patients who have failed or who are intolerant to other antifungal therapies. Ketoconazole tablets are not indicated for the treatment of onychomycosis, cutaneous dermatophyte infections, Candida infections or f ungal meningitis.