Lubiprostone (Amitiza®) is a medication used to treat chronic idiopathic constipation, irritable bowel syndrome with constipation (IBS-C), and opioid-induced constipation. It works by increasing the secretion of fluid in the intestines, which softens stools and promotes regular bowel movements. Amitiza helps relieve symptoms such as abdominal discomfort, bloating, and straining, improving overall digestive function.